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The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling

Articolo
Data di Pubblicazione:
2018
Abstract:
Paediatric low-grade gliomas (pLGGs) are a heterogeneous group of brain tumours associated with a high overall survival: however, they are prone to recur and supratentorial lesions are difficult to resect, being associated with high percentage of disease recurrence. Our aim was to shed light on the biology of pLGGs.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
PI3K/AKT/mTORC1; paediatric low-grade gliomas; miR-139-5p; microRNAs; patients’ derived primary cells; supratentorial
Elenco autori:
Catanzaro, Giuseppina; Besharat, Zein Mersini; Miele, Evelina; Chiacchiarini, Martina; Po, Agnese; Carai, Andrea; Marras, Carlo Efisio; Antonelli, Manila; Badiali, Manuela; Raso, Alessandro; Mascelli, Samantha; Schrimpf, Daniel; Stichel, Damian; Tartaglia, Marco; Capper, David; von Deimling, Andreas; Giangaspero, Felice; Mastronuzzi, Angela; Locatelli, Franco; Ferretti, Elisabetta
Autori di Ateneo:
CATANZARO GIUSEPPINA
Link alla scheda completa:
https://iris.unilink.it/handle/20.500.14085/9225
Pubblicato in:
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Journal
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