Radiogenic angiosarcoma of the breast (Rasb): A case and imaging features

Radiogenic angiosarcoma of the breast (RASB) is a rare late sequela of breast irradiation following breast-conserving surgery for invasive breast cancer and carries a poor prognosis; it is a rare finding and the clinical presentation is uncharacteristic; often present as multiple, distinct lesions. Diagnosis is made by an abnormal mammogram, ultrasound, or MRI resulting in a core biopsy [1]; mammography may not have any suspicious findings, and ultrasound findings are nonspecific in one-third of patients [2].Surgery is the mainstay of treatment for localized disease while systemic chemotherapy and re-irradiation are appropriate for women with disseminated or recurrent RASB with a good long-term outcome in selected cases [6]. We present the case of a 82 yo woman with RASB, poorly indifferentiated angiosarcoma of the left breast, after a history of invasive ductal cancer of the left breast, treated in 2007 with quadrantectomy, linphoadenectomy and radiotherapy.