The effects of muscle hypotonia and weakness on balance: a study on Prader-Willi and Ehlers-Danlos syndrome patients
Academic Article
Publication Date:
2011
abstract:
Prader–Willisyndrome(PWS)andEhlers–Danlossyndrome(EDS)aretwodifferentgeneticaldisordersbothcharacterized,amongotherfeatures,bymuscularhypotonia.Posturalcontrolseemstobeimpairedinbothconditions.Theaimofthepresentstudywasto quantitativelycompareposturalcontrolinadultPWSandEDSusingstabilometricplatformtounveilpossiblecommondeterminantsofimpairedbalance.Weenrolled11PWS and21EDSadultpatientsand20age-matchedcontrols.Theywereinstructedtomaintainanuprightstandingpositionfor30swithopeneyes(OEs)focusingona6cmblack circlepositionedatadistanceof1.5m.Both PWSandEDSpatientswerecharacterizedbyhigherRANGEML,RANGEAPandtrajectorylengthofCoPvaluesascomparedtoCG.NostatisticallydifferenceswerefoundbetweenPWSandEDSintermsofanyoftheseparameters.Theresultsdemonstratedthatboth PWSandEDSarecharacterizedbyasevereposturalinstability.Musclehypotoniaandweaknessmayaccountforreducedbalancecapacity.Quantitativecharacterizationofinstabilityisimportanttoidentify,developandenhancerehabilitationinterventions.
Iris type:
1.1 Articolo in rivista
Keywords:
Prader–Willi; Ehlers–Danlos; Posture
List of contributors:
Galli, M; Cimolin, V; Vismara, L; Grugni, G; Camerota, F; Celletti, C; Albertini, G; Rigoldi, C; Capodaglio, P
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